Prozac Chemical Structure
Fluoxetine hydrochloride is the hydrochloride salt form of fluoxetine a diphenhydramine derivative and selective serotonin reuptake inhibitor with antidepressant antiobsessional and antibulimic effects.
Prozac chemical structure. R fluoxetine hydrochloride 98 hplc solid. The chemical formula of prozac is c 17 h 18 f 3 no. N methyl 3 phen yl 3 α la α trifl uoro p tolyl oxy pr opylamine. An n methyl 3 phenyl 3 4 trifluoromethyl phenoxy propan 1 amine that has r configuration the antidepressant drug fluoxetine is a racemate comprising equimolar amounts of r and s fluoxetine.
Prozac wiki sarafem wiki fluoxetine. Fluoxetine sold under the brand names prozac and sarafem among others is an antidepressant of the selective serotonin reuptake inhibitor ssri class. It is an enantiomer of a r fluoxetine. An n methyl 3 phenyl 3 4 trifluoromethyl phenoxy propan 1 amine that has s configuration the antidepressant drug fluoxetine is a racemate comprising equimolar amounts of r and s fluoxetine.
Prozac works by delaying the reuptake of serotonin so the serotonin that is released lasts longer. 3r n methyl 3 phenyl 3 4 trifluoromethyl phenoxy propan 1 amine hydrochloride. Fluoxetine binds to the presynaptic serotonin receptor resulting in negative allosteric modulation of the receptor complex thereby blocking recycling of serotonin by the presynaptic receptor. 1 german acd iupac name n methyl 3 phenyl 3 4 trifluormethyl phenoxy propan 1 a minhydrochlorid.
3r n methyl 3 phenyl 3 4 trifluoromethyl phenoxy propan 1 aminium chloride. The oral bioavailability of fluoxetine is 90 as a result of hepatic first pass metabolism l7721 in a bioequivalence study the cmax of fluoxetine 20 mg for the established reference formulation was 11 754 ng ml while the cmax for the proposed generic formulation was 11 786 ng ml a185285 fluoxetine is very lipophilic and highly plasma protein bound allowing the drug and it s active metabolite norfluoxetine to be distributed to the brain l7721. It may decrease the risk of suicide in those over the age of 65. N methyl 3 p trifl uoromethylphenoxy 3 phenylpropylamine hydrochloride.
N methyl 3 p p trifluoromethylphe noxy 3 phenylpropy lamine. It is used for the treatment of major depressive disorder obsessive compulsive disorder ocd bulimia nervosa panic disorder and premenstrual dysphoric disorder.
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