Polydipsia Algorithm
The patient returned with continued polydipsia and polyuria and repeat labs in table 1.
Polydipsia algorithm. If results remain inconclusive a water deprivation test is indicated. Risperidone and olanzapine improved polydipsia in case reports but prospective double blind studies have not shown any benefit with olanzapine. The workup for polyuria and polydipsia can be tedious time consuming expensive confusing and not without significant patient morbidity especially in those cases with normal or near normal blood work. Urine osmolarity was 119 mosm kg ucr 26 una 16 uk 6 and ucl less than 20 all units meq l.
Serum osmolarity was elevated to 294 mosm kg. A systematic review of the ability of urine concentration to distinguish antipsychotic from psychosis induced hyponatremia. Copeptin in the differential diagnosis of the polydipsia polyuria syndrome revisiting the direct and indirect water deprivation tests. Please note that formulations routes and doses may differ between drug names and brands drug formularies or locations.
Fenske w quinkler m lorenz d zopf k haagen u papassotiriou j pfeiffer af fassnacht m störk s allolio b. The algorithm is based on identifying signs that suggest complications of underlying somatic disease objectifying polydipsia and analysis of urine and blood specimens. Millard md and maegen dupper md atsariyasing w goldman mb. Algorithms charts polydipsia.
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