Low Anion Gap

If your doctor says you have a low anion gap you might have a lower than normal amount of acid in your blood. Albumin is one of. If the result derived from value of electrolyte suggests low anion gap the test is usually repeated as there may be a laboratory error.

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Albumin is both a protein and an anion.

Low anion gap. Potential causes and diagnosis of a low anion gap laboratory error. Besides laboratory error the other cause of low anion can be hypoalbuminemia. Hypoalbuminemia means that there are low levels of a protein albumin in your blood. Normally anion gap results.

Albumin is a negatively charged protein and its loss from the serum results in the retention of other negatively charged ions such as chloride and bicarbonate. In a study of over 67 000 calculations of the anion gap the prevalence of a low anion gap value was found in only 304 0 8 out of the 39 360 patients whose electrolyte blood levels were studied and only 19 of them had a repeatedly low anion gap. When a person has too much acid or too little base in their blood the anion gap will be. This value which compares the concentration of positively charged ions in the blood to negatively charged ions in the blood can become abnormal by a number of metabolic derangements.

If your test indicates a low anion gap value your doctor may order a second test to account for. Low anion gap is rarely found. Causes of a high anion gap. If the anion gap level is too low this can mean that the person has hyponatremia a decreased level of sodium in the blood.

Some other potential causes of a low anion gap are as follows 2 38 39. A low anion gap is frequently caused by hypoalbuminemia. It is less amount of albumin in the body. Causes test and treatment causes of a low anion gap.

As bicarbonate and chloride anions are used to calculate the anion gap there is a subsequent decrease in the gap. People can have a low anion gap for a number of reasons. It can also mean that the person has multiple myeloma which is cancer of the. The most common cause of a low anion gap level is a lack of albumin protein in the blood or hypoalbuminemia when immunoglobulin levels are increased.

This result isn t common and sometimes it s due to a lab error. Having low levels of albumin a negatively charged protein can cause a decreased anion gap. An electrolyte blood test is used to calculate an anion gap. Your doctor may ask.